Program

Conference Program in PDF Format

2010 DEUEL Program Chair

Peter Tontonoz
University of California, Los Angeles
Email:ptontonoz@mednet.ucla.edu

2010 DEUEL Program Co-Chair

Kathryn J. Moore
Harvard Medical School Lipid Metabolism Unit, Massachusetts General Hospital
Email:kmoore@molbio.mgh.harvard.edu

2010 Deuel Conference on Lipids, March 3-5, 2010
Laguna Cliffs Marriott Resort, Dana Point, CA

Preliminary Conference Program

Tuesday, March 2, 4:00 PM to 9:00 PM
Registration, Reception, and Dinner

Wednesday, March 3, 8:45 AM to 12:30 PM
Session Leader: Kathryn J. Moore

Session 1         Macrophage Signaling in Lipid Metabolism and Disease
8:30-9:05The path to macrophage foam cell formation
Kathryn J. Moore, New York University, New York

9:05-9:40Tissue macrophages in inflammation-induced insulin resistance and dyslipidemia
Jerrold Olefsky, University of California, San Diego

9:40-10:00Atherosclerosis and apoptosis in Abcg1-/-ApoE-/- mice
Elizabeth Tarling, University of California, Los Angeles

10:00-10:20 Coffee Break

10:20-10:55Mechanisms of Atherosclerotic Lesion Regression
Edward Fisher, New York University, New York

10:55-11:30Fatty acids and Acyl-CoAs, Macrophages, and Atherosclerosis
Karin E. Bornfeldt, University of Washington, Seattle

11:30-11:50Characterization of oxidized lipids in cholesterol-fed zebrafish
Yuri Miller, University of California, San Diego

Wednesday, March 3, 7:30 to 9:30 PM
Session Leader: Peter Tontonoz

The Havel Lecture
            Nuclear receptor control of lipid metabolism
David J. Mangelsdorf, University of Texas Southwestern Medical Center, Dallas

Wine reception and Trainees’ Poster Session

Poster Board dimension: 4’ high x 6’ wide, with useable board space measuring: 44.5” h x 69" w.

Thursday, March 4, 8:45 AM to 12:30 PM
Session Leader: Jay Horton

Session 2         Mechanisms of Metabolic Control
8:30-9:05 Fat regulation in C. elegans
Kaveh Ashrafi, University of California, San Francisco

9:05-9:40 Lipins: Multifunctional lipid phosphatases
Karen Reue, University of California, Los Angeles

9:40-10:00Cavin-2 is a cell surface cholesterol sensor linking caveolae to the cytoskeleton
Michael Breen, Boston University, Boston

10:00-10:20 Coffee Break

10:20-10:55 "Oxysterol regulation of cholesterol homeostasis
Daniel Ory, Washington University, St. Louis

10:55-11:30 "New insights into mechanisms for ER-associated degradation of HMG CoA reductase
Russell Debose-Boyd, University of Texas Southwestern Medical Center, Dallas

10:55-11:30 "Syndecan-1 mediated uptake of triglyceride-rich lipoproteins
Erin Foley, University of California, San Diego

 

Thursday, March 4, 7:30 to 9:30 PM
Session Leader: Joseph Witztum

Session 3         Systemic Approaches to Metabolic Disease

7:30-8:05 “Metabolic mechanisms of tissue failure in type 2 diabetes”
Christopher Newgard, Duke University

8:05-8:40Hypothalamic regulation of energy balance
Randy Seeley, University of Cincinnati

8:40-9:15Endothelial Control of Metabolism
Jorge Plutzky, Brigham and Women’s Hospital, Boston

9:15-9:35FGF15/19 and FGF21 govern fed and fasted responses in the liver
Matthew Potthoff, University of Texas Southwestern, Dallas

 

Friday, March 5, 8:30 AM to 12:00 noon
Session Leader: Steven G. Young

Session 4         Human Metabolism and Therapeutic Opportunities
8:30-9:05 The JLR Lecture: “Functional analysis of new genes regulating plasma lipoproteins
Daniel J. Rader, University of Pennsylvania, Philadelphia

9:05-9:40New Connections Between Insulin Resistance, Diabetes and Cholesterol Metabolism
C. Ronald Kahn, Joslin Diabetes Center, Harvard Medical School

9:40-10:00 Coffee Break

10:00-10:35 "Inflammation, adipocytes and modulation of HDL”
Muredach Reilly, University of Pennsylvania, Philadelphia

10:35-11:10Antisense Inhibition of ApoB:From Bench to Clinic
Rosanne M. Crooke, Isis Pharmaceuticals, Carlsbad

11:10-11:45 “Therapeutic potential of FGF-21”
Murielle Veniant-Ellison, Amgen, Thousand Oaks